Machine Learning in Pediatric Critical Care

Machine Learning (ML) (or Artificial Intelligence AI) is trending. Publications with regard to ML are on the increase in medical literature.

Specifically critical care medicine generates huge amounts of detailed data. In a recent article steps are described to enable use of ML in daily clinical practice. This blog will describes an actual working implementation of the first step in ML to be used in clinical practice.


Mamdani, M., & Slutsky, A. S. (2020). Artificial intelligence in intensive care medicine. Intensive Care Medicine, 47(2), 147–149. http://doi.org/10.1007/s00134-020-06203-2

Continue reading “Machine Learning in Pediatric Critical Care”

Feliz indentation and Fantomas

Indentation is important in F#, as it defines the code blocks and the separate code elements. Using Feliz to define a view, in a Fable.React application, the indentation matters just as much, and even more.

Fantomas is a beautiful tool that automatically formats your code and ensures consistency, also in indentation. But using code like with the Feliz library, there some serious drawbacks.

Continue reading “Feliz indentation and Fantomas”

Machine Learning Feature Selection

In a previous post, a setup using an F# script to perform machine learning with Microsoft.ML is described. A very import aspect for a successful model is picking the right features that will predict the label, i.e. the exposure that is associated with outcome. In this post a simple F# feature selection algorithm is described that automatically figures out which features result in the ‘best’ model.

Continue reading “Machine Learning Feature Selection”

First Microsoft.ML steps!

Machine learning is the new kid on the block and has become accessible with the advent of the Microsoft.ML library. In medicine machine learning hasn’t been used that much. Most scientific epidemiological research still relies on established statistical analysis. The core principle, however, is the same. Known exposure is used to predict outcome. In Pediatric Intensive Care, prediction of mortality is used to benchmark and monitor performance. In the Netherlands, for this purpose, data is gathered at a national basis. This blog will discuss a machine learning setup to analyze data using a data set with 13.793 PICU admissions.

Continue reading “First Microsoft.ML steps!”

Testing an Event Driven Design of a Resuscitation Protocol

In a previous post a described an event driven domain design to run a resuscitation protocol. I also mentioned that running this protocol in practice can have some pitfalls. One of these pitfalls is the use of a defibrillator that is required to apply a cardio conversion by delivering a shock. We have to test that this cannot ever occur.

Continue reading “Testing an Event Driven Design of a Resuscitation Protocol”

Event Driven Design of a Resuscitation app

For some time now I have been thinking of writing an app to help with running a resuscitation protocol. The resuscitation protocol as provided by the Dutch Advanced Pediatric Life Support is rather straight forward. Yet to adhere to this protocol in a stressful situation for a patient with a life threatening condition is a challenge to many physicians or health care providers.

Continue reading “Event Driven Design of a Resuscitation app”